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Article

Assessing the impact of non-differential genotyping errors on rare variant tests of association.

Human heredity - 1 Jan 2011

Powers Scott, Gopalakrishnan Shyam, Tintle Nathan

Abstract excerpt

BACKGROUND/AIMS: We aim to quantify the effect of non-differential genotyping errors on the power of rare variant tests and identify those situations when genotyping errors are most harmful. METHODS: We simulated genotype and phenotype data for a range of sample sizes, minor allele frequencies, disease relative risks and numbers of rare variants. Genotype errors were then simulated using five different error...

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Identifiers

PMID: 22004945
DOI: 10.1159/000332222
PMCID: PMC3214826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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