Article
Association of ataxia telangiectasia mutated (ATM) gene mutation/deletion with rhabdomyosarcoma.
Cancer biology & therapy - 1 Jan 2000
Zhang Peilin, Bhakta Kunjan S, Puri Pier Lorenzo, Newbury Robert O, Feramisco James R, Wang Jean Y
Abstract excerpt
Rhabdomyosarcoma is a common malignancy in children. There are two major types of rhabdomyosarcomas, the embryonal and the alveolar, differing in cytogenetic and morphologic features. The alveolar type of rhabdomyosarcoma is frequently associated with chromosome translocation t(2; 13) and poor clinical prognosis. Pathogenesis of rhabdomyosarcoma remains obscure, and especially it occurs in the location where...
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