Article
Clinicopathologic and survival correlates of embryonal rhabdomyosarcoma driven by RAS/RAF mutations.
Genes, chromosomes & cancer - 1 Mar 2022
Agaram Narasimhan P, Huang Shih-Chiang, Tap William D, Wexler Leonard H, Antonescu Cristina R
Abstract excerpt
Embryonal rhabdomyosarcoma (ERMS) is the most common subtype of rhabdomyosarcoma (RMS). Among RMS subtypes, ERMS is associated with a favorable outcome with an overall survival of 70% at 5 years for localized disease. The molecular profile of ERMS is heterogeneous, including mostly point mutations in various genes. Therapeutic strategies have remained relatively consistent irrespective of the molecular...
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