Article
DNA repair systems in rhabdomyosarcoma.
Histology and histopathology - 1 Aug 2013
Tsioli Panagiota G, Patsouris Efstratios S, Giaginis Constantinos, Theocharis Stamatios E
Abstract excerpt
Rhabdomyosarcoma (RMS) represents the most common soft tissue sarcoma in children and adolescent population. There are two major histological subtypes, embryonal (ERMS) and alveolar (ARMS), differing in cytogenetic and morphological features. RMS pathogenesis remains controversial and several cellular mechanisms and pathways have been implicated. Application of intense chemo- and radio-therapy improves survival...
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