Article
A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcoma
1 Jun 2000
Abstract excerpt
Rhabdomyosarcomas are the most common soft-tissue sarcoma found in children. The alveolar subtype is clinically more aggressive than the embryonal subtype. In addition to the presence of specific chromosome translocations and associated fusion gene products in a high proportion of the alveolar subtype, we previously showed that tumors with this histology frequently show evidence of genomic amplification. Here, we...
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