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Article

Molecular pathogenesis of rhabdomyosarcoma.

Cancer biology & therapy - 1 Jan 2000

Xia Shujuan J, Pressey Joseph G, Barr Frederic G

Abstract excerpt

Rhabdomyosarcoma (RMS) is a family of soft tissue tumors that are associated with the skeletal muscle lineage and generally occur in the pediatric population. Based on histopathologic features, two subtypes, embryonal (ERMS) and alveolar (ARMS), were identified and associated with distinct clinical characteristics and genetic alterations. ARMS is associated with 2;13 or 1;13 chromosomal translocations, which...

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Source

Identifiers

PMID: 12170781
DOI: 10.4161/cbt.51

Genes

CDK4
MDM2
PAX3
PAX7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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