Article
Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency.
Nature genetics - 1 May 2003
Paw Barry H, Davidson Alan J, Zhou Yi, Li Rong, Pratt Stephen J, Lee Charles, Trede Nikolaus S, Brownlie Alison, Donovan Adriana, Liao Eric C, Ziai James M, Drejer Anna H, Guo Wen, Kim Carol H, Gwynn Babette, Peters Luanne L, Chernova Marina N, Alper Seth L, Zapata Agustin, Wickramasinghe Sunitha N, Lee Matthew J, Lux Samuel E, Fritz Andreas, Postlethwait John H, Zon Leonard I
Abstract excerpt
Most eukaryotic cell types use a common program to regulate the process of cell division. During mitosis, successful partitioning of the genetic material depends on spatially coordinated chromosome movement and cell cleavage. Here we characterize a zebrafish mutant, retsina (ret), that exhibits an erythroid-specific defect in cell division with marked dyserythropoiesis similar to human congenital...
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