Article
Loss of DIAPH3, a Formin Family Protein, Leads to Cytokinetic Failure Only under High Temperature Conditions in Mouse FM3A Cells.
International journal of molecular sciences - 11 Nov 2020
Kazama Hiroki, Kashiwaba Shu-Ichiro, Ishii Sayaka, Yoshida Keiko, Yatsuo Yuta, Naraoka Takuma, Fukuoka Masashi, Murakami Yasufumi
Abstract excerpt
Cell division is essential for the maintenance of life and involves chromosome segregation and subsequent cytokinesis. The processes are tightly regulated at both the spatial and temporal level by various genes, and failures in this regulation are associated with oncogenesis. Here, we investigated the gene responsible for defects in cell division by using murine temperature-sensitive (ts) mutant strains, tsFT101...
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