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Article

hnRNP I is required to generate the Ca2+ signal that causes egg activation in zebrafish.

Development (Cambridge, England) - 1 Sept 2009

Mei Wenyan, Lee Karen W, Marlow Florence L, Miller Andrew L, Mullins Mary C

Abstract excerpt

Egg activation is an important cellular event required to prevent polyspermy and initiate development of the zygote. Egg activation in all animals examined is elicited by a rise in free Ca(2+) in the egg cytosol at fertilization. This Ca(2+) rise is crucial for all subsequent egg activation steps, such as cortical granule exocytosis, which modifies the vitelline membrane to prevent polyspermy. The cytosolic...

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Identifiers

PMID: 19666827
DOI: 10.1242/dev.037879
PMCID: PMC2723070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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