Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new role of glutathione peroxidase 4 during human erythroblast enucleation

19 Nov 2020

Abstract excerpt

The selenoprotein glutathione peroxidase 4 (GPX4), the only member of the glutathione peroxidase family able to directly reduce cell membrane-oxidized fatty acids and cholesterol, was recently identified as the central regulator of ferroptosis. GPX4 knockdown in mouse hematopoietic cells leads to hemolytic anemia and to increased spleen erythroid progenitor death. The role of GPX4 during human erythropoiesis is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Research and Pathophysiology
Share to Erythrocyte Function and Pathophysiology
Share to Neonatal Health and Biochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33211827
DOI: 10.1182/bloodadvances.2020003100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new role of glutathione peroxidase 4 during human erythroblast enucleationPMID 33211827Read ↗

New insights into the mechanisms of red blood cell enucleation: From basics to clinical applicationsSemantic proximity Read ↗

GPX4: old lessons, new featuresSemantic proximity Read ↗

A pooled CRISPR screen reveals genes critical for erythroblast enucleationSemantic proximity Read ↗

Mouse embryonic stem cell‐derived motor neurons are susceptible to ferroptosisSemantic proximity Read ↗

Comprehensive Proteomic Analysis of Human ErythropoiesisSemantic proximity Read ↗

The role of Selenoprotein N in the differentiation of erythroid progenitors during stress erythropoiesisSemantic proximity Read ↗

Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration.Semantic proximity Read ↗

Comprehensive Characterization and Global Transcriptome Analyses of Human Fetal Liver Terminal ErythropoiesisSemantic proximity Read ↗

Autophagy facilitates organelle clearance during differentiation of human erythroblastsSemantic proximity Read ↗

Erythropoietin Mediates Glycerophospholipid Remodeling During Human Early ErythropoiesisSemantic proximity Read ↗

Downregulation of Mitochondrial TSPO Inhibits Mitophagy and Reduces Enucleation during Human Terminal Erythropoiesis.Semantic proximity Read ↗

Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.