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Article

A yeast homologue of Hsp70, Ssa1p, regulates turnover of the MFA2 transcript through its AU-rich 3' untranslated region.

Molecular and cellular biology - 1 Apr 2003

Duttagupta Radharani, Vasudevan Shobha, Wilusz Carol J, Peltz Stuart W

Abstract excerpt

Many eukaryotic mRNAs exhibit regulated decay in response to cellular signals. AU-rich elements (AREs) identified in the 3' untranslated region (3'-UTR) of several such mRNAs play a critical role in controlling the half-lives of these transcripts. The yeast ARE-containing mRNA, MFA2, has been studied extensively and is degraded by a deadenylation-dependent mechanism. However, the trans-acting factors that promote...

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Identifiers

PMID: 12665566
DOI: 10.1128/MCB.23.8.2623-2632.2003
PMCID: PMC152564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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