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Article

Suppression of an Hsp70 mutant phenotype in Saccharomyces cerevisiae through loss of function of the chromatin component Sin1p/Spt2p.

Journal of bacteriology - 1 Dec 1998

Baxter B K, Craig E A

Abstract excerpt

The Ssa subfamily of Hsp70 molecular chaperones in the budding yeast Saccharomyces cerevisiae has four members, encoded by SSA1, SSA2, SSA3, and SSA4. Deletion of the two constitutively expressed genes, SSA1 and SSA2, results in cells which are slow growing and temperature sensitive. In this study, we demonstrate that an extragenic suppressor of the temperature sensitivity of ssa1 ssa2 strains, EXA1-1, is a...

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Identifiers

PMID: 9851990
DOI: 10.1128/JB.180.24.6484-6492.1998
PMCID: PMC107749

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