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Article

Control of human beta-globin mRNA stability and its impact on beta-thalassemia phenotype.

Haematologica - 1 Jun 2011

Peixeiro Isabel, Silva Ana Luísa, Romão Luísa

Abstract excerpt

Messenger RNA (mRNA) stability is a critical determinant that affects gene expression. Many pathways have evolved to modulate mRNA stability in response to developmental, physiological and/or environmental stimuli. Eukaryotic mRNAs have a considerable range of half-lives, from as short as a few minutes to as long as several days. Human globin mRNAs constitute an example of highly stable mRNAs. However, a wide...

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Identifiers

PMID: 21357703
DOI: 10.3324/haematol.2010.039206
PMCID: PMC3105653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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