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Article

Reassembly and protection of small nuclear ribonucleoprotein particles by heat shock proteins in yeast cells.

RNA (New York, N.Y.) - 1 Dec 1999

Bracken A P, Bond U

Abstract excerpt

The process of mRNA splicing is sensitive to in vivo thermal inactivation, but can be protected by pretreatment of cells under conditions that induce heat-shock proteins (Hsps). This latter phenomenon is known as "splicing thermotolerance". In this article we demonstrate that the small nuclear ribonucleoprotein particles (snRNPs) are in vivo targets of thermal damage within the splicing apparatus in heat-shocked...

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Identifiers

PMID: 10606269
DOI: 10.1017/s1355838299991203
PMCID: PMC1369880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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