Article
AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation.
Genes & development - 1 Oct 1997
Fan X C, Myer V E, Steitz J A
Abstract excerpt
AU-rich elements (AREs, usually containing repeated copies of AUUUA), when present in the 3'-untranslated regions (UTRs) of many mammalian mRNAs, confer instability on their host RNA molecules. The viral small nuclear RNA (snRNA) Herpesvirus saimiri U RNA 1 (HSUR 1) also contains an AUUUA-rich se...
Topics
- Antigens, Surface
- Base Sequence
- ELAV Proteins
- ELAV-Like Protein 1
- Gene Expression Regulation
- Genes, Reporter
- Globins
- Herpesvirus 2, Saimiriine
- Molecular Sequence Data
- Mutation
- RNA, Messenger
- RNA, Small Nuclear
- RNA, Viral
- RNA-Binding Proteins
- Repetitive Sequences, Nucleic Acid
- Ribonucleases
- Transcription, Genetic
- Transfection