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Article

AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation.

Genes & development - 1 Oct 1997

Fan X C, Myer V E, Steitz J A

Abstract excerpt

AU-rich elements (AREs, usually containing repeated copies of AUUUA), when present in the 3'-untranslated regions (UTRs) of many mammalian mRNAs, confer instability on their host RNA molecules. The viral small nuclear RNA (snRNA) Herpesvirus saimiri U RNA 1 (HSUR 1) also contains an AUUUA-rich sequence. Here, we report that this ARE induces rapid degradation of HSUR 1 itself and of other snRNAs including HSUR 2...

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Source

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Identifiers

PMID: 9334320
DOI: 10.1101/gad.11.19.2557
PMCID: PMC316563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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