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Article

Isolation and characterization of extragenic suppressors of mutations in the SSA hsp70 genes of Saccharomyces cerevisiae.

Genetics - 1 Jun 1992

Nelson R J, Heschl M F, Craig E A

Abstract excerpt

Saccharomyces cerevisiae strains that contain null alleles of two hsp70 genes, SSA1 and SSA2, are temperature sensitive for growth. In this study, extragenic suppressors of ssa1 ssa2 have been isolated. Suppression is due to mutations at nuclear loci designated EXA1, EXA2 and EXA3 for EXtragenic suppressor hsp70 subfamily A. Two of the four EXA1 alleles are dominant as is EXA3-1. The other two EXA1 alleles as...

Topics

Alleles
Fungal Proteins
Gene Expression Regulation, Fungal
Genes, Dominant
Genes, Fungal
Genes, Suppressor
Genetic Linkage
Heat-Shock Proteins
Recombinant Proteins
Saccharomyces cerevisiae

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Identifiers

PMID: 1644272
DOI: 10.1093/genetics/131.2.277
PMCID: PMC1205003

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1644272-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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