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Article

Detection of target nucleic acids and proteins by amplification of circularizable probes.

Expert review of molecular diagnostics - 1 Mar 2003

Zhang David Y, Liu Bin

Abstract excerpt

Circularizable oligonucleotide probe (C-probe) is a unique molecule that offers significant advantages over conventional probes. Closed circular structure can be formed through ligation of its ends after hybridizing onto a target and locked on its target due to the helical turns formed between the complementary sequences of the target and the C-probe (padlock probe). Under an isothermal condition, C-probe can be...

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Identifiers

PMID: 12647998
DOI: 10.1586/14737159.3.2.237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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