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Article

Rolling-circle amplification in DNA diagnostics: the power of simplicity.

Expert review of molecular diagnostics - 1 Nov 2002

Demidov Vadim V

Abstract excerpt

Due to its robustness and simplicity, the rolling replication of circular DNA probes holds a distinct position in DNA diagnostics among other isothermal methods of target, probe or signal amplification. Major rolling-circle amplification approaches to DNA detection via posthybridization probe/signal turn-by-turn enhancement are briefly overviewed here with an emphasis on the new concepts and latest progress in...

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DNA, Circular
DNA-Directed DNA Polymerase
DNA Probes
DNA Replication
DNA, Single-Stranded
Forecasting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Amplification

Templates, Genetic

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PMID: 12465451
DOI: 10.1586/14737159.2.6.542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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