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Article

Detection of nucleic acid targets using ramified rolling circle DNA amplification: a single nucleotide polymorphism assay model.

PloS one - 1 Jan 2013

Smith James H, Beals Thomas P

Abstract excerpt

BACKGROUND: Isothermal amplification methods provide alternatives to PCR that may be preferable for some nucleic acid target detection tasks. Among current isothermal target detection methods, ramified rolling circle amplification (RAM) of single-stranded DNA circles that are formed by ligation of linear DNA probes (C-probes or padlock probes) offers a unique target detection system by linked primers and a simple...

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Identifiers

PMID: 23724122
DOI: 10.1371/journal.pone.0065053
PMCID: PMC3664557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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