Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chemiluminescent detection of DNA hybridization and single-nucleotide polymorphisms on a solid surface using target-primed rolling circle amplification.

The Analyst - 1 Sept 2008

Li Zhengping, Li Wei, Cheng Yongqiang, Hao Longteng

Abstract excerpt

A new chemiluminescent (CL) method has been developed for the sensitive detection of DNA hybridization and single-nucleotide polymorphisms (SNPs) with target-primed rolling circle amplification (RCA). The capture oligonucleotide probe is firstly immobilized on a polystyrene well plate and then hybridized with the wild DNA target. A designed padlock probe is circularized after perfect hybridization to the DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Circular
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to In Situ Hybridization

Share to Luminescent Measurements

Share to Nucleic Acid Amplification Techniques

Share to Oligonucleotide Probes

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 18709189
DOI: 10.1039/b807368f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chemiluminescent detection of DNA hybridization and single-nucleotide polymorphisms on a solid surface using target-primed rolling circle amplification.PMID 18709189Read ↗

Homogeneous and label-free fluorescence detection of single-nucleotide polymorphism using target-primed branched rolling circle amplification.Semantic proximity Read ↗

Colorimetric detection of single-nucleotide mutations based on rolling circle amplification and G-quadruplex-based DNAzyme.Semantic proximity Read ↗

Novel biosensing methodologies for improving the detection of single nucleotide polymorphism.Semantic proximity Read ↗

Rolling circle amplification combined with gold nanoparticle aggregates for highly sensitive identification of single-nucleotide polymorphisms.Semantic proximity Read ↗

Ligation-mediated rolling-circle amplification-based approaches to single nucleotide polymorphism detection.Semantic proximity Read ↗

Ligase chain reaction coupled with rolling circle amplification for high sensitivity detection of single nucleotide polymorphisms.Semantic proximity Read ↗

Ligation-rolling circle amplification combined with γ-cyclodextrin mediated stemless molecular beacon for sensitive and specific genotyping of single-nucleotide polymorphism.Semantic proximity Read ↗

Visual detection of single-nucleotide polymorphism with hairpin oligonucleotide-functionalized gold nanoparticles.Semantic proximity Read ↗

Amplification of circularizable probes for the detection of target nucleic acids and proteins.Semantic proximity Read ↗

A label-free strategy for SNP detection with high fidelity and sensitivity based on ligation-rolling circle amplification and intercalating of methylene blue.Semantic proximity Read ↗

Detection of target nucleic acids and proteins by amplification of circularizable probes.Semantic proximity Read ↗

A simple and ultrasensitive fluorescence assay for single-nucleotide polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.