Genetics of hereditary diffuse gastric cancer: progress and future challenges.

doi:10.2217/14796694.2.3.363

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Article

Genetics of hereditary diffuse gastric cancer: progress and future challenges.

Future oncology (London, England) - 1 Jun 2006

Suriano Gianpaolo, Ferreira Paulo, Mateus Ana Rita, Correia Joana, Henriques Lara, Seruca Raquel

Abstract excerpt

Hereditary diffuse gastric cancer (HDGC) is a rare cancer susceptibility syndrome. One third of HDGC syndrome families carry germline mutations of the E-cadherin gene. Owing to the limitation of the current endoscopic screening techniques and since no chemoprevention is yet available, total proph...

Topics

Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Neoplastic Syndromes, Hereditary
Stomach Neoplasms

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