Article
Hereditary diffuse gastric cancer.
Cancer treatment and research - 1 Jan 2010
Schrader Kasmintan, Huntsman David
Abstract excerpt
Gastric cancer is one of the world's leading causes of cancer mortality. A small percentage of cases can be attributed to heritable mutations in highly penetrant cancer susceptibility genes. In this chapter we will focus on the genetic cause of hereditary diffuse gastric cancer (HDGC). Until 10 years ago, individuals from these families lived with the uncertainty of developing lethal gastric cancer. Today, HDGC...
Topics
- Antigens, CD
- Cadherins
- DNA Mutational Analysis
- Family Health
- Gastrectomy
- Genetic Counseling
- Genetic Predisposition to Disease
- Genetic Testing
- Genetic Variation
- Heterozygote
- Humans
- Medical Oncology