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Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research

30 Jun 2010

Abstract excerpt

25-30% of families fulfilling the criteria for hereditary diffuse gastric cancer have germline mutations of the CDH1 (E-cadherin) gene. In light of new data and advancement of technologies, a multidisciplinary workshop was convened to discuss genetic testing, surgery, endoscopy and pathology reporting. The updated recommendations include broadening of CDH1 testing criteria such that: histological confirmation of...

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PMID: 20591882
DOI: 10.1136/jmg.2009.074237

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