Article
Mutations in the putative HR-C region of the measles virus F2 glycoprotein modulate syncytium formation.
Journal of virology - 1 Apr 2003
Plemper Richard K, Compans Richard W
Abstract excerpt
The fusion (F) glycoproteins of measles virus strains Edmonston (MV-Edm) and wtF (MV-wtF) confer distinct cytopathic effects and strengths of hemagglutinin (H) interaction on a recombinant MV-Edm virus. They differ in just two amino acids, V94 and V101 in F-Edm versus M94 and F101 in F-wtF, both of which lie in the relatively uncharacterized F(2) domain. By comparing the sequence of MV F with those of the...
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