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Article

NOTCH4 and the frontal lobe in schizophrenia.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2003

Wassink Thomas H, Nopoulos Peggy, Pietila Jennifer, Crowe Raymond R, Andreasen Nancy C

Abstract excerpt

NOTCH4 is a developmentally expressed gene recently reported to be in linkage disequilibrium (LD) with schizophrenia. We investigated this finding in our sample of subjects, focusing on an exonic (CTG)(n) polymorphism, examining not only the association of this polymorphism with the disease phenotype, but also its effect on frontal lobe brain morphology and cognitive function in both affected individuals and a...

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Source

Identifiers

PMID: 12627456
DOI: 10.1002/ajmg.b.10071

Genes

NOTCH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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