Characterization of a single nucleotide polymorphism in the lipopolysaccharide binding protein and its association with sepsis.

Abstract excerpt

We sought to characterize polymorphisms in the proximal coding region of the lipopolysaccharide binding protein gene and to determine whether a previously reported variant was associated with sepsis complicated by organ failure or shock after trauma. We used multiple analytical methods, including pyrosequencing, restriction fragment length polymorphism, and sequencing to characterize the proximal coding region....

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