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Article

The presence of functionally relevant toll-like receptor polymorphisms does not significantly correlate with development or outcome of sepsis.

Genetic testing and molecular biomarkers - 1 Sept 2011

Ahmad-Nejad Parviz, Denz Christof, Zimmer Wilma, Wacker Jennifer, Bugert Peter, Weiss Christel, Quintel Michael, Neumaier Michael

Abstract excerpt

AIMS: Members of the toll-like receptor (TLR) family have been shown to play important roles in inflammatory responses. Single-nucleotide polymorphisms (SNPs) altering receptor activity may either have detectable effects or might be without results due to compensatory mechanisms. We determined the genotype frequencies of functionally relevant SNPs in TLR2, 4 and 5 in critically ill patients (n=150) from a...

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Identifiers

PMID: 21721932
DOI: 10.1089/gtmb.2010.0258

Genes

TLR2
TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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