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Article

HLA-A Locus is Associated With Sepsis and Septic Shock After Traumatic Injury.

Annals of surgery - 1 Jan 2022

Horn Dara L, Mindrinos Michael, Anderson Kirsten, Krishnakumar Sujatha, Wang Chunlin, Li Ming, Hollenbach Jill, O'Keefe Grant E

Abstract excerpt

OBJECTIVE: Determine whether variation in the HLA region is associated with the development of post-traumatic sepsis and septic shock. BACKGROUND: Sepsis-related deaths remain a major source of mortality after traumatic injury. Genetic characteristics may contribute to susceptibility to adverse outcomes including sepsis and septic shock. Recent advances in next-generation sequencing technology now allow...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33064392
DOI: 10.1097/SLA.0000000000003932
PMCID: PMC10060028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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