Article
Aryl hydrocarbon receptor regulates growth, but not atresia, of mouse preantral and antral follicles.
Biology of reproduction - 1 May 2003
Benedict Jamie C, Miller Kimberly P, Lin Tien-Min, Greenfeld Chuck, Babus Janice K, Peterson Richard E, Flaws Jodi A
Abstract excerpt
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that binds various environmental contaminants. Despite our knowledge regarding the role of the AhR in mediating toxicity, little is known about the physiological role of the AhR. Previous studies indicate that the AhR may regulate folliculogenesis, because AhR-deficient (AhRKO) mice have fewer preantral and antral follicles than...
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