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Article

Maternal High-Fat Diet-Induced Loss of Fetal Oocytes Is Associated with Compromised Follicle Growth in Adult Rat Offspring.

Biology of reproduction - 1 Apr 2016

Tsoulis Michael W, Chang Pauline E, Moore Caroline J, Chan Kaitlyn A, Gohir Wajiha, Petrik James J, Vickers Mark H, Connor Kristin L, Sloboda Deborah M

Abstract excerpt

Maternal obesity predisposes offspring to metabolic and reproductive dysfunction. We have shown previously that female rat offspring born to mothers fed a high-fat (HF) diet throughout pregnancy and lactation enter puberty early and display aberrant reproductive cyclicity. The mechanisms driving this reproductive phenotype are currently unknown thus we investigated whether changes in ovarian function were...

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Identifiers

PMID: 26962114
DOI: 10.1095/biolreprod.115.135004
PMCID: PMC4861169

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AMH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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