Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri

21 Nov 2007

Abstract excerpt

Maternal smoking during pregnancy is associated with a variety of adverse neonatal outcomes including altered reproductive performance. Herein we provide molecular evidence for a pathway involved in the elimination of the female germline due to prepregnancy and/or lactational exposure to polycyclic aromatic hydrocarbons (PAHs), environmental toxicants found in cigarette smoke. We show that ovaries of offspring...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Effects and risks of endocrine disrupting chemicals
Share to Toxic Organic Pollutants Impact

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18037991
DOI: 10.1172/jci28493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of HarakiriPMID 18037991Read ↗

Induction of proapoptotic gene expression and recruitment of p53 herald ovarian follicle loss caused by polycyclic aromatic hydrocarbons.Semantic proximity Read ↗

Nicotine exposure is associated with targeted impairments in primordial follicle phenotype in cultured neonatal mouse ovaries.Semantic proximity Read ↗

Maternal Smoke Exposure Impairs the Long-Term Fertility of Female Offspring in a Murine Model1Semantic proximity Read ↗

In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling.Semantic proximity Read ↗

Cigarette Smoke Exposure Leads to Follicle Loss via an Alternative Ovarian Cell Death Pathway in a Mouse ModelSemantic proximity Read ↗

Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction.Semantic proximity Read ↗

Ovarian Toxicity of 4-Vinylcyclohexene Diepoxide: A Mechanistic ModelSemantic proximity Read ↗

Implications of environmental toxicants on ovarian follicles: how it can adversely affect the female fertility?Semantic proximity Read ↗

Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM2.5) depletes the ovarian follicle reserve and causes sex-dependent cardiovascular changes in apolipoprotein E null miceSemantic proximity Read ↗

Bisphenol A exposure modulates reproductive and endocrine system, mitochondrial function and cellular senescence in female adult rats: A hallmarks of polycystic ovarian syndrome phenotype.Semantic proximity Read ↗

Programmed Cell Death in the Ovary: Insights and Future Prospects Using Genetic TechnologiesSemantic proximity Read ↗

Effects of deletion of the transcription factor Nrf2 and benzo [a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.