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Article

Lesions of aryl-hydrocarbon receptor-deficient mice.

Veterinary pathology - 1 Nov 1997

Fernandez-Salguero P M, Ward J M, Sundberg J P, Gonzalez F J

Abstract excerpt

We have analyzed the possible role of the aryl-hydrocarbon receptor (AHR) in the aging process of mice using a homozygous null mouse (Ahr-/-) line as a model. We studied 52 male and female Ahr-/- mice aged from 6-13 months. Forty-six percent died or were ill by 13 months of age. Ahr-/- mice developed age-related lesions in several organs, some of which were apparent after only 9 months of age. Cardiovascular...

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Source

Identifiers

PMID: 9396142
DOI: 10.1177/030098589703400609

Genes

AHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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