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Article

Errors and linkage disequilibrium interact multiplicatively when computing sample sizes for genetic case-control association studies.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2003

Gordon D, Levenstien M A, Finch S J, Ott J

Abstract excerpt

Single nucleotide polymorphisms (SNP) may be used in case-control designs to test for association between a SNP marker and a disease. Such designs may assume that the genotype data are reported without error. Our goal is quantifying the effects that errors have on sample size for case-control studies with haplotypes formed by a disease locus and a SNP marker locus in the presence of linkage disequilibrium (LD)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12603052
DOI: 10.1142/9789812776303_0046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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