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Histone modifications at the blastocyst Axin1(Fu) locus mark the heritability of in vitro culture-induced epigenetic alterations in mice.

Biology of reproduction - 1 Nov 2010

Fernandez-Gonzalez Raul, Ramirez Miguel A, Pericuesta Eva, Calle Alexandra, Gutierrez-Adan Alfonso

Abstract excerpt

For epigenetic phenotypes to be passed on from one generation to the next, it is required that epigenetic marks between generations are not cleared during the two stages of epigenetic reprogramming: mammalian gametogenesis and preimplantation development. The molecular nature of the chromatin marks involved in these events is unknown. Using the epigenetically inherited allele Axin1(Fu) (the result of a...

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PMID: 20650886
DOI: 10.1095/biolreprod.110.084715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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