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Article

A second component of HLA-linked susceptibility to type 1 diabetes maps to class I region.

Annals of the New York Academy of Sciences - 1 Oct 2006

Kawabata Yumiko, Ikegami Hiroshi, Fujisawa Tomomi, Noso Shinsuke, Asano Katsuaki, Hiromine Yoshihisa, Ogihara Toshio

Abstract excerpt

Type 1 diabetes is a polygenic disease with a major susceptibility locus, IDDM1, located in the human leukocyte antigen (HLA) region. Although class II loci, DR and DQ genes in particular, are major components of IDDM1, accumulating lines of evidence indicated that IDDM1 consists of multiple components and that non-class II genes in addition to class II genes contribute to susceptibility to and/or age-at-onset of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

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Share to HLA-DR Antigens

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 17130566
DOI: 10.1196/annals.1375.042

Genes

MICA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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