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Article

The p75 receptor is required for BDNF-induced differentiation of neural precursor cells.

Biochemical and biophysical research communications - 21 Feb 2003

Hosomi Sanae, Yamashita Toshihide, Aoki Miwa, Tohyama Masaya

Abstract excerpt

Epidermal growth factor (EGF)-treated neurospheres from fetal forebrain contain multipotential cells capable of neuronal, astrocytic, and oligodendroglial differentiation. These neural precursor cells express the TrkB as well as the neurotrophin receptor p75 (p75NTR), suggesting that they are BDNF responsive. In this study, we test whether the p75NTR plays a role in the differentiation of these neural precursor...

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Source

Identifiers

PMID: 12589813
DOI: 10.1016/s0006-291x(03)00077-9

Genes

BDNF
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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