Article
Expression of the low-affinity neurotrophin receptor, p75(NTR), is upregulated by oligodendroglial progenitors adjacent to the subventricular zone in response to demyelination.
Glia - 1 Oct 2004
Petratos Steven, Gonzales Michael F, Azari Michael F, Marriott Mark, Minichiello Rebecca A, Shipham Kylie A, Profyris Christos, Nicolaou Antonis, Boyle Kristy, Cheema Surindar S, Kilpatrick Trevor J
Abstract excerpt
Precursor cells have the capacity to repopulate the demyelinated brain, but the molecular mechanisms that facilitate their recruitment are largely unknown. The low-affinity neurotrophin receptor, p75(NTR), may be one of these regulators; however, its expression profile by oligodendroglia within the multiple sclerosis (MS) brain remains uncertain. We therefore assessed the expression profile of this receptor...
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