Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment of an epidermal growth factor-dependent, multipotent neural precursor cell line.

In vitro cellular & developmental biology. Animal - 1 Jan 2000

Nakagaito Y, Satoh M, Kuno H, Iwama T, Takeuchi M, Hakura A, Yoshida T

Abstract excerpt

We have established a multipotent clonal cell line, named MEB5, from embryonic mouse forebrains after the infection of a retrovirus carrying E7 oncogene of human papillomavirus type 16. MEB5 cells proliferated in serum-free, epidermal growth factor (EGF)-supplemented medium. They expressed marker...

Topics

Animals
Astrocytes
Cell Differentiation
Cell Division
Cell Line, Transformed
Cell Survival
Culture Media, Serum-Free
Epidermal Growth Factor
Mice
Mice, Inbred C3H
Oncogene Proteins, Viral
Papillomaviridae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Papillomavirus E7 Proteins

Phenotype

Prosencephalon

Retroviridae

Source

Identifiers

PMID: 9719419
DOI: 10.1007/s11626-998-0119-5

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9719419-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment of an epidermal growth factor-dependent, multipotent neural precursor cell line.PMID 9719419Read ↗

AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression.Semantic proximity Read ↗

Neuroectodermal differentiation from mouse multipotent adult progenitor cells.Semantic proximity Read ↗

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor.Semantic proximity Read ↗

Characterization of a multipotent neural progenitor cell line cloned from an adult p53-/- mouse cerebellum.Semantic proximity Read ↗

Characterization of A2B5+ glial precursor cells from cryopreserved human fetal brain progenitor cells.Semantic proximity Read ↗

Phenotypic and morphological characterization of in vitro oligodendrogliogenesis.Semantic proximity Read ↗

A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes.Semantic proximity Read ↗

Combination of hTERT and bmi-1, E6, or E7 Induces Prolongation of the Life Span of Bone Marrow Stromal Cells from an Elderly Donor without Affecting Their Neurogenic PotentialSemantic proximity Read ↗

NG2 and Olig2 expression provides evidence for phenotypic deregulation of cultured central nervous system and peripheral nervous system neural precursor cells.Semantic proximity Read ↗

EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells.Semantic proximity Read ↗

In Vitro Models for Neurogenesis.Semantic proximity Read ↗

Generation of human cortical neurons from a new immortal fetal neural stem cell line.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.