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Article

Establishment of an epidermal growth factor-dependent, multipotent neural precursor cell line.

In vitro cellular & developmental biology. Animal - 1 Jan 2000

Nakagaito Y, Satoh M, Kuno H, Iwama T, Takeuchi M, Hakura A, Yoshida T

Abstract excerpt

We have established a multipotent clonal cell line, named MEB5, from embryonic mouse forebrains after the infection of a retrovirus carrying E7 oncogene of human papillomavirus type 16. MEB5 cells proliferated in serum-free, epidermal growth factor (EGF)-supplemented medium. They expressed markers for neural precursor cells (nestin, A2B5, and RC1) and did not express markers for neurons (class III beta-tubulin),...

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Identifiers

PMID: 9719419
DOI: 10.1007/s11626-998-0119-5

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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