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Article

mRNAs encoding telomerase components and regulators are controlled by UPF genes in Saccharomyces cerevisiae.

Eukaryotic cell - 1 Feb 2003

Dahlseid Jeffrey N, Lew-Smith Jodi, Lelivelt Michael J, Enomoto Shinichiro, Ford Amanda, Desruisseaux Michelle, McClellan Mark, Lue Neal, Culbertson Michael R, Berman Judith

Abstract excerpt

Telomeres, the chromosome ends, are maintained by a balance of activities that erode and replace the terminal DNA sequences. Furthermore, telomere-proximal genes are often silenced in an epigenetic manner. In Saccharomyces cerevisiae, average telomere length and telomeric silencing are reduced by loss of function of UPF genes required in the nonsense-mediated mRNA decay (NMD) pathway. Because NMD controls the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12582130
DOI: 10.1128/EC.2.1.134-142.2003
PMCID: PMC141172

Genes

STN1
TEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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