Article
Cell cycle-dependent transcription factors control the expression of yeast telomerase RNA.
RNA (New York, N.Y.) - 1 Jul 2013
Dionne Isabelle, Larose Stéphanie, Dandjinou Alain T, Abou Elela Sherif, Wellinger Raymund J
Abstract excerpt
Telomerase is a specialized ribonucleoprotein that adds repeated DNA sequences to the ends of eukaryotic chromosomes to preserve genome integrity. Some secondary structure features of the telomerase RNA are very well conserved, and it serves as a central scaffold for the binding of associated proteins. The Saccharomyces cerevisiae telomerase RNA, TLC1, is found in very low copy number in the cell and is the...
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