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Article

A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews.

American journal of human genetics - 1 Mar 2003

Sugimura Kazuhito, Taylor Kent D, Lin Ying-chao, Hang Tieu, Wang Dai, Tang Yong-Ming, Fischel-Ghodsian Nathan, Targan Stephan R, Rotter Jerome I, Yang Huiying

Abstract excerpt

Crohn disease (CD) exhibits a 2-4-fold increased frequency in Jews as compared with other ethnic/racial groups. Three coding variants of the NOD2/CARD15 have been reported as independent disease-predisposing mutations (DPMs), but these were found in only 30%-40% of patients with CD and could not account for all the linkage between CD and the IBD1 locus. The aim of the present study was to explore whether...

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Identifiers

PMID: 12577202
DOI: 10.1086/367848
PMCID: PMC1180227

Genes

NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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