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Article

NOD2/CARD15 genotype and phenotype differences between Ashkenazi and Sephardic Jews with Crohn's disease.

The American journal of gastroenterology - 1 Jun 2004

Karban Amir, Waterman Matti, Panhuysen Carolien I, Pollak Rivka Dresner, Nesher Shula, Datta Lisa, Weiss Batia, Suissa Alain, Shamir Raanan, Brant Steven R, Eliakim Rami

Abstract excerpt

OBJECTIVE: NOD2/CARD15 has been identified as a major susceptibility gene for Crohn's disease (CD). Three mutations, Arg702Trp, Gly908Arg, and Leu1007fsinsC, are associated with CD. The incidence and prevalence rate of inflammatory bowel diseases is two- to four-fold higher in Ashkenazi Jews as compared to non-Jewish Caucasians. The aim of this study was to determine the significance of the NOD2/CARD15 mutations...

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Source

Identifiers

PMID: 15180737
DOI: 10.1111/j.1572-0241.2004.04156.x

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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