Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of 22 genetic variants with Crohn's disease risk in the Ashkenazi Jewish population: a case-control study.

BMC medical genetics - 6 May 2011

Peter Inga, Mitchell Adele A, Ozelius Laurie, Erazo Monica, Hu Jianzhong, Doheny Dana, Abreu Maria T, Present Daniel H, Ullman Thomas, Benkov Keith, Korelitz Burton I, Mayer Lloyd, Desnick Robert J

Abstract excerpt

BACKGROUND: Crohn's disease (CD) has the highest prevalence among individuals of Ashkenazi Jewish (AJ) descent compared to non-Jewish Caucasian populations (NJ). We evaluated a set of well-established CD-susceptibility variants to determine if they can explain the increased CD risk in the AJ population. METHODS: We recruited 369 AJ CD patients and 503 AJ controls, genotyped 22 single nucleotide polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Genetics, Population

Share to Multivariate Analysis

Share to Regression Analysis

Share to ROC Curve

Source

Open in PubMed Open full text

Identifiers

PMID: 21548950
DOI: 10.1186/1471-2350-12-63
PMCID: PMC3212904

Genes

IRGM
NOD2
PTGER4
PTPN2
STAT3
TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of 22 genetic variants with Crohn's disease risk in the Ashkenazi Jewish population: a case-control study.PMID 21548950Read ↗

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.Semantic proximity Read ↗

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.Semantic proximity Read ↗

Insights into the genetic epidemiology of Crohn’s and rare diseases in the Ashkenazi Jewish populationSemantic proximity Read ↗

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.Semantic proximity Read ↗

Crohn's Disease: Genetics Update.Semantic proximity Read ↗

Rare coding variant analysis in a large cohort of Ashkenazi Jewish families with inflammatory bowel disease.Semantic proximity Read ↗

Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis.Semantic proximity Read ↗

Rare and common variant discovery in complex disease: the IBD case studySemantic proximity Read ↗

Inflammatory bowel disease: genetic and epidemiologic considerations.Semantic proximity Read ↗

Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease.Semantic proximity Read ↗

Identifying novel high-impact rare disease-causing mutations, genes and pathways in exomes of Ashkenazi Jewish inflammatory bowel disease patientsSemantic proximity Read ↗

A population-based case-control study of CARD15 and other risk factors in Crohn's disease and ulcerative colitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.