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Article

NOD2/CARD15 mutation analysis and genotype-phenotype correlation in Jewish pediatric patients compared with adults with Crohn's disease.

The Journal of pediatrics - 1 Aug 2004

Weiss Batia, Shamir Raanan, Bujanover Yoram, Waterman Mati, Hartman Corina, Fradkin Akiva, Berkowitz Drora, Weintraub Ilana, Eliakim Ram, Karban Amir

Abstract excerpt

OBJECTIVES: The allelic variants in the NOD2/CARD15 gene G908R, R702W, and 1007fs are strongly and independently associated with susceptibility to Crohn's disease (CD). Our aim was to compare the NOD2/CARD15 genotype and the genotype-phenotype correlation in Jewish pediatric patients with CD (</=16 years of age) with older patients with CD. STUDY DESIGN: Carrier frequencies of the three variants were determined...

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Source

Identifiers

PMID: 15289769
DOI: 10.1016/j.jpeds.2004.05.024

Genes

NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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