Article
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.
The American journal of gastroenterology - 1 Dec 2004
Economou Michael, Trikalinos Thomas A, Loizou Konstantinos T, Tsianos Epameinondas V, Ioannidis John P A
Abstract excerpt
OBJECTIVES: Three variants of the CARD15/NOD2 gene (SNP8, SNP12, and SNP13) have been associated with Crohn's disease (CD). We assessed the impact of NOD2 variants on the CD risk across diverse populations and examined possible associations with disease phenotype. METHODS: We performed a metaanalysis searching MEDLINE and EMBASE (last search 05/2004) and contacting field experts. RESULTS: Forty-two eligible...
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