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Article

CARD15/NOD2 risk alleles in the development of Crohn's disease in the Australian population.

Annals of human genetics - 1 Jan 2003

Cavanaugh J A, Adams K E, Quak E J, Bryce M E, O'Callaghan N J, Rodgers H J, Magarry G R, Butler W J, Eaden J A, Roberts-Thomson I C, Pavli P, Wilson S R, Callen D F

Abstract excerpt

We have previously reported strong evidence for linkage between IBD1 and Crohn's disease (CD) in Australian Crohn's disease families. Three risk alleles for Crohn's disease, (Arg702Trp (C/T), Gly908Arg (G/C) and 980fs981 (-/C), were recently identified in the CARD15/NOD2 gene on chromosome 16, implicating this as the IBD1 locus. Using a novel diagnostic PCR-RFLP, we have examined the frequency of these alleles in...

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Source

Identifiers

PMID: 12556233
DOI: 10.1046/j.1469-1809.2003.00006.x

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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