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Article

A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission.

Proceedings of the National Academy of Sciences of the United States of America - 4 Feb 2003

Ho Angela, Morishita Wade, Hammer Robert E, Malenka Robert C, Sudhof Thomas C

Abstract excerpt

Mints (also called X11-like proteins) are adaptor proteins composed of divergent N-terminal sequences that bind to synaptic proteins such as CASK (Mint 1 only) and Munc18-1 (Mints 1 and 2) and conserved C-terminal PTB- and PDZ-domains that bind to widely distributed proteins such as APP, presenilins, and Ca(2+) channels (all Mints). We find that Mints 1 and 2 are similarly expressed in most neurons except for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12547917
DOI: 10.1073/pnas.252774899
PMCID: PMC298786

Genes

CASK
APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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