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Article

MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Nov 2010

Hussain Natasha K, Hsin Honor, Huganir Richard L, Sheng Morgan

Abstract excerpt

Misshapen/NIKs (Nck-interacting kinases)-related kinase (MINK) and closely related TRAF2/Nck-interacting kinase (TNIK) are proteins that specifically bind to activated Rap2 and are thus hypothesized to relay its downstream signal transduction. Activated Rap2 has been found to stimulate dendritic...

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Share to Dendrites
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Share to Potassium Channels, Voltage-Gated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Serine-Threonine Kinases

Share to rap GTP-Binding Proteins

Share to Rats, Sprague-Dawley

Share to Receptors, AMPA

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Source

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Identifiers

PMID: 21048137
DOI: 10.1523/JNEUROSCI.4124-10.2010
PMCID: PMC3070943

Genes

TNIK
TRAF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21048137-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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