Article
Distinct LIN-10 domains are required for its neuronal function, its epithelial function, and its synaptic localization.
Molecular biology of the cell - 1 Mar 2005
Glodowski Doreen R, Wright Tricia, Martinowich Keri, Chang Howard Chia-Hao, Beach Douglas, Rongo Christopher
Abstract excerpt
alpha-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors (AMPARs) mediate excitatory neurotransmission at neuronal synapses, and their regulated localization plays a role in synaptic plasticity. In Caenorhabditis elegans, the PDZ and PTB domain-containing protein LIN-10 is required both for the synaptic localization of the AMPAR subunit GLR-1 and for vulval fate induction in...
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