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Article

Generation of hepatocytes expressing functional cytochromes P450 from a pancreatic progenitor cell line in vitro.

The Biochemical journal - 15 Mar 2003

Marek Carylyn J, Cameron Gary A, Elrick Lucy J, Hawksworth Gabrielle M, Wright Matthew C

Abstract excerpt

The proliferating AR42J-B13 pancreatic cell line is known to respond to glucocorticoid treatment by producing foci of cells that express the liver-specific albumin gene. We demonstrate that this cell line also expresses liver-specific or liver-enriched functional cytochrome P450 proteins when stimulated to trans-differentiate into hepatocytes by glucocorticoid. These data suggest that this cell line has an...

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Identifiers

PMID: 12542397
DOI: 10.1042/BJ20021545
PMCID: PMC1223247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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